Bioregenerative Treatments in Columbus
At Columbus Facial Plastics, we’re excited to offer cutting-edge bioregenerative treatments, also called biostimulators, for patients seeking a natural approach to younger-looking skin. These innovative treatments work by harnessing your body’s own healing abilities, rather than relying on synthetic substances, to refresh and rejuvenate your skin. Our Columbus biostimulator treatments include traditional PRP (platelet-rich plasma), advanced PRF (platelet-rich fibrin), and EZGel for comprehensive facial rejuvenation.

Number of Treatments | 3 sessions spaced 6-8 weeks apart |
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Treatment Areas | Face, under-eyes, and other areas needing rejuvenation |
Treatment Time | 60-90 minutes including blood draw and processing |
Recovery Time | Minimal, potential mild swelling or bruising for up to a week |
Considerations |
Results develop gradually over 2-3 months as collagen builds. Initial treatments provide subtle improvements that become more noticeable over time. |
Results | Natural-looking rejuvenation with improved skin quality |
Lasting Effects | 6-12 months depending on treatment area and individual response |
Cost | PRP/PRF starting at $735 when added to other procedures, EZGel $1,000 for comprehensive facial application |

Why Choose Columbus Facial Plastics for Natural Collagen Stimulation
- Natural results using your body’s own growth factors and regenerative capabilities
- Versatile options that can be used alone or to enhance other procedures
- Reduced downtime when combined with lasers or microneedling treatments
- Suitable for delicate areas like under the eyes where traditional fillers present challenges
- Customized approach based on your specific skin goals
“Using your own body to stimulate collagen provides more long-term, sustainable, and natural results with fewer complications. When you use bioregenerative treatments, you’re not just addressing immediate concerns, but helping prevent that collagen breakdown that naturally occurs as we age.” –Shireen Shatti, CNP
PRP (Platelet-Rich Plasma)
PRP uses your body’s own concentrated healing factors, drawn from a small sample, to rejuvenate your skin. After spinning the blood in a specialized centrifuge, we isolate the platelet-rich plasma–a clear, yellowish serum packed with growth factors. When combined with microneedling or laser treatments, these growth factors accelerate healing and stimulate collagen production, enhancing your results while reducing downtime.
Benefits of PRP in Columbus
- Well-researched treatment with years of proven effectiveness
- Enhances skin tone, texture, and overall appearance with natural healing factors
- Excellent for hair restoration treatments
- Reduces recovery time after laser treatments and microneedling procedures
- Creates a noticeable “glow effect” as skin regenerates and rejuvenates
PRF (Platelet-Rich Fibrin)
PRF takes regenerative therapy a step further. Unlike PRP, PRF preserves the natural clotting capabilities in your blood. The fibrin creates a matrix that acts as a natural scaffold to support gradual, sustained release of growth factors. This slow-release approach is ideal for delicate areas, particularly the under-eye region where skin renewal happens more slowly. PRF supports a more robust wound healing response, leading to improved skin quality, enhanced collagen production, and a natural-looking refreshed appearance that develops progressively over time.
Benefits of PRF in Columbus
- Slow, sustained release of regenerative growth factors
- Fibrin matrix creates a natural scaffold for tissue regeneration
- Potentially longer-lasting results than traditional PRP for select procedures
- Excellent for under-eye rejuvenation
- Superior collagen response for smoother, healthier skin
PRF EZGel
EZGel is our most advanced bioregenerative treatment that transforms your own blood into a gel-like substance with volumizing capabilities. A portion of the plasma is heated to create a filler-like consistency. Once cooled, it is combined with traditional PRF to create a natural injectable that provides immediate volume while stimulating long-term collagen production. This innovative approach offers a completely natural alternative to synthetic fillers, particularly for delicate areas like under the eyes. For optimal results, we recommend 3 sessions scheduled 6-8 weeks apart.
Benefits of Columbus EZGel Treatments
- 100% natural alternative to synthetic fillers
- Safe for sensitive areas like the under eyes without the side effects of traditional hyaluronic acid fillers
- Immediate volumizing effect and long-term collagen production
- Can be used in areas where traditional fillers may not be effective
- Yields significantly more product than standard PRF
5-Step Process for Getting Started With Biostimulator Treatments in Columbus:
- 1.Schedule a consultation to discuss your rejuvenation goals
- 2.Determine which bioregenerative treatment is right for your specific concerns
- 3.Explore potential combination treatments to maximize your results
- 4.Plan your treatment with adequate time before any major events
- 5.Prepare for your session by staying well-hydrated
5-Step Process for Success With Your Treatment:
- Undergo a simple blood draw to collect the sample for your treatment
- Allow 30 minutes for processing while your skin is prepped or numbed
- Receive your customized treatment via topical application or injection
- Follow post-treatment care instructions for optimal results
- Return for follow-up treatments as recommended (typically 3 sessions, 6-8 weeks apart)

Enhance Your Results With Add-On Services
Add PRP or PRF to reduce healing time and boost collagen.
Bioregenerative treatments post-Halo or BBL reduce downtime and speed up recovery.
EZGel can be placed where Sculptra presents challenges, such as around the eyes and mouth, creating comprehensive rejuvenation.
Pair traditional fillers with PRP or PRF for both immediate and long-lasting volume.
Pricing for Bioregenerative Treatments
PRP and PRF treatments start at $735 when added to other procedures. Standalone EZGel treatments are $1,000 for a comprehensive facial application. A series of three treatments spaced 6-8 weeks apart is typically recommended for optimal results. Your initial consultation fee can be applied toward your treatment.
FREQUENTLY ASKED QUESTIONS ABOUT COLUMBUS BIOREGENERATIVE TREATMENTS:
- PRP is a liquid containing concentrated platelets and anticoagulants. PRP yields more liquid than PRF, making it ideal for broad applications or procedures with longer handling times.
- PRF is a fibrin-rich matrix without anticoagulants, offering slower, sustained release of growth factors.
- EZ Gel is a gel-like mixture of PRF and thickened plasma proteins, providing natural volume and collagen stimulation.
Downtime is minimal. When paired with lasers or microneedling, biostimulators often reduce recovery time. EZGel injections may cause mild swelling or bruising, similar to filler treatments.
Results vary by treatment type. A subtle glow often appears shortly after treatment. Collagen production takes place over 2-3 months. EZ Gel offers some immediate volume, though not as dramatic as synthetic fillers, with progressive improvement over time as collagen develops.
Results are progressive and cumulative. A series of three treatments is typically recommended initially, followed by maintenance treatments. Results can last 6-12 months depending on the treatment area and individual healing response.
Most people are excellent candidates, especially those seeking natural alternatives to fillers, under-eye rejuvenation in Columbus, or enhanced outcomes from other aesthetic treatments. We’ll evaluate your candidacy during your consultation.
EZGel can be an excellent way to “preview” what filler might look like in certain areas of your face. Many patients use EZGel to simulate the appearance of traditional fillers before making a longer-term commitment. Since EZGel breaks down more naturally and quickly than hyaluronic acid fillers, it gives you a chance to see if you like the appearance of added volume in specific areas without the 1-2 year commitment of traditional fillers. This “try before you buy” approach is particularly valuable for first-time patients or those considering treatment in new areas. If you love the results, you can either continue with EZGel treatments or transition to longer-lasting filler options with confidence.